The rushing modern lifestyle of most people has a lot of disadvantages. Fast food, unhealthy habits, poor diet, on-the-go snacking, smoking, and ongoing stress have a negative impact on the mucous membranes of the organs. All these facts cause a bunch of health problems, one of which is stomach ache. An unhealthy lifestyle will eventually result in the development of stomach ulcers or reflux esophagitis. One should consult a gastroenterologist if they have pain after eating, nausea, sour belching, or excessive gas production.
If you face stomach problems, most often you’ll be advised to take Omeprazole as your main medicine. We will help you learn more about this drug, its composition, side effects and contraindications, the composition of medicine, etc.
Composition and mechanism of action
Omeprazole medication is an antiulcer drug that inhibits the proton pump. It lowers the frequency of recurrent gastrointestinal bleeding and provides immediate and efficient hydrochloric acid inhibition. It also protects the mucous membranes of the stomach and duodenum from injury.
The medication lessens the amount of hydrochloric acid in the stomach and the amount released after meals. This enables you to lessen acidity and get rid of unpleasant symptoms including nausea, frequent sour belching, and heaviness and pain in the stomach.
The drug produces ideal circumstances for the elimination of H. pylori, which is frequently responsible for gastritis and peptic ulcers, by causing a sustained reduction in acidity. It’s important to remember that omeprazole remains inactive until it hits the stomach’s acidic environment. Omeprazole considerably enhances patient well-being and provides rapid recovery from stomach and duodenum illnesses caused by acidity. The drug lowers the risk of complications and recurrence and generally improves the health of patients. The medicine shows its effect already 1 hour after consumption moreover, it is effective during the whole day.
Omeprazole is based on an active ingredient that has the same name. Usually, it is produced in the form of pills, but it also could be found in the form of powder for an infusion solution that is exclusively utilized in a hospital environment. This pump inhibitor could be found under different brand names. Since excipients used by different drug manufacturers vary, it is impossible to create a universal list.
Omeprazole Prices
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| Dosage | Pills | Canadian pharmacy price | Other pharmacies price |
| 10 mg | 10 | $7.20 | $10.79 |
| 10 mg | 30 | $18.30 | $27.59 |
| 10 mg | 60 | $32.40 | $52.79 |
| 10 mg | 90 | $47.70 | $73.19 |
| 20 mg | 30 | $26.40 | $39.59 |
| 20 mg | 60 | $43.20 | $64.79 |
| 20 mg | 90 | $63.90 | $94.79 |
| 20 mg | 120 | $84.00 | $113.99 |
| 40 mg | 30 | $48.90 | $62.39 |
| 40 mg | 60 | $78.60 | $99.59 |
| 40 mg | 90 | $114.30 | $145.19 |
| 40 mg | 120 | $136.80 | $172.79 |
Intake Conditions
Omeprazole aids in shielding the injured stomach mucosa from an adverse environment. Omeprazole is frequently prescribed by doctors as part of complicated treatments for pancreatitis and heartburn. There are several conditions in which omeprazole may be prescribed for upper gastrointestinal disorders. The following conditions are indications for use:
- chronic duodenal ulcers of the digestive tract;
- reflux esophagitis;
- increased acidity;
- heartburn;
- Zollinger-Ellison syndrome;
- ulcers and erosion during therapy with anti-inflammatory drugs;
- polyendocrine adenomatosis;
- uncomplicated heartburn that lasts longer than two days during the week.
Also, the drug can be prescribed not only for treatment but also for the prevention of heartburn, gastric, and duodenal ulcers. In this case, only 20 mg of the drug per day is needed. In some cases, 10 mg may be sufficient, in others, the dosage can be increased to 40 mg per day.
How to take Omeprazole
The medicine is determined to be taken before food, usually before breakfast.
The pills should be swallowed without chewing in order not to damage the integrity of the shell. The drug can be dissolved in yogurt or juice. If the medication needs to be taken many times throughout the day, it is typically recommended to take it in the evening.
Omeprazole is permitted to dissolve in acidified water, yogurt, or juice (15–20 ml) for people with swallowing problems or youngsters. The ready mixture should be used during 30 minutes max. Omeprazole can be given intravenously or by a catheter directly into the stomach when the patient has a critical condition, particularly if they are in the intensive care unit. The recommended dosage for intravenous administration is 40 mg once a day as a 20–30 minute infusion.
| Disease | Treatment duration | Dosage |
| Gastrointestinal peptic ulcer in the acute phase | 1–2 months | 20–40mg/per day. The dose is divided into 2 doses |
| Erosive and ulcerative esophagitis | Until full recovery | 20–40mg/per day. The dose is divided into 2 doses. As an anti-relapse treatment, 20 mg/day is prescribed |
| Duodenal ulcer | 2–4 weeks | 20 mg/day |
| Gastropathy and erosive and ulcerative lesions caused by anti-inflammatory drugs | 4–8 weeks | 20 mg/day |
| H. pylori eradication | 7 days | 20 mg of the drug 2 times / day.
Omeprazole is taken with antibacterial agents |
| Relief of uncomplicated heartburn | 14 days. A second course of treatment is possible after 4 months | 20 mg/day. |
| Reflux esophagitis | 4 weeks | 20 mg/day. |
| Ulcerogenic adenoma of the pancreas | Until full recovery | 20–120 mg (if the dose exceeds 80 mg / day, it should be divided into 2–3 doses) |
| Zollinger-Ellison Syndrome | Until full recovery | The dose of Omeprazole is selected strictly individually: from 60 to 120 mg 2 times / day. |
| To prevent leakage of acidic gastric contents into the esophagus during long operations | On the eve of surgery and 2–4 hours before it | 40 mg/day |
Side Effects
Omeprazole is usually well-tolerated, but sometimes it can cause some adverse effects. The most widespread are:
- allergic reactions: rash, hives;
- headache and dizziness;
- drowsiness and lethargy;
- hypochromic anemia in children;
- visual disturbances;
- hearing loss;
- nausea and vomiting;
- constipation or diarrhea;
- increased gas formation;
- muscle pain.
Even though Omeprazole rarely causes side effects, you should bear in mind that some contradictions do not support the drug assumption. Among them are:
- Hypersensitivity to the drug’s ingredients
- Intolerance to fructose and lactose.
- Lack of sucrase;
- Kid’s age up to 4 years old, excluding extreme circumstances;
- Pregnancy and lactation;
- Kidney and liver failure.